Depends on the look I want and the mood I'm trying to convey. Maybe two people in profile, nearly silhouette, is what I want. Maybe two people against a bright blown-out window is what I want. Maybe I want them balanced because something is happening outside the window that I want the audience to see.
If you're asking for some generic example, though I don't like to think generically, most people would say that on film, two to three stops overexposed looks natural for the view out the window -- bright but with detail. Now on video, it may or may not hold detail even only two stops overexposed, so you have to be more careful.
But it really depends on how big the window is and how much of the frame it takes up, etc. And the mood you are trying to create.