Shoot frontally, not in profile (obviously). Use a longer focal length lens and keep the camera height at eye level, not low.
Otherwise, just don't throw a strong nose shadow. Completely flat, frontal soft lighting, as is used in actors' head shots, will make the nose almost disappear if that's what you want, but I would rather retain some character to the face and just minimize anything distracting, not erase it altogether.
Even soft side-lighting might be fine if it is soft enough.
Just the other day I was looking at some magazine photos of the pretty actress in "Nacho Libre" and noticed that in side angles, she has a somewhat "crooked" nose (not sideways-crooked, but it flattens out near the bridge, not a straight line), but you can't tell at all in the frontal angles.
